SDCE holds classes at six main campuses as well as numerous off-campus locations.
| Name | Abbreviation | Address | Associated Campus |
|---|---|---|---|
| U.S. Naval Hospital | NHOSP | 34800 Bob Wilson Dr./Balboa Park, San Diego, CA | Centre City |
| Union of Pan Asian Communities | UNPAC | 5348 University Ave., San Diego, CA | Mid City |
| Union of Pan Asian Communities | UPACS | 3288 El Cajon Blvd., Suite #13, San Diego, CA | Mid City |
| Union of Pan Asian Communities | UPACC | 1031 25th St., San Diego, CA | Centre City |
| United Cerebral Palsy Association | UCPRP | 10405 San Diego Mission Rd., San Diego, CA | North City |
| United Cerebral Palsy Association | UNCER | 3821 Calle Fortunada, San Diego, CA | North City |
| University Avenue Baptist Church | UNIBC | 6060 University Ave., San Diego, CA | Mid City |
| University Care Center | UNICC | 5602 University Ave., San Diego, CA | Mid City |
| University City High School | UNICY | 6949 Genesee Avenue, San Diego, CA | West City |
| UPAC East Wind | EWSOC | 2359 Ulric St., San Diego, CA | North City |
| US Naval Station 32nd Street | USN32 | E Harbor Dr & S 32nd St., San Diego, CA | Centre City |